Reforming the global financial system offers a historic opportunity to accelerate Africa’s urban development and economic integration. Although Public Development Banks (PDBs) make up just 5% of the global financial sector, they manage nearly US$23 trillion in assets and play a vital role in financing long-term development. For African cities—among the fastest-growing in the world—reform could unlock access to affordable, concessional financing for infrastructure, climate adaptation, and social services. By ensuring fairer lending practices, improving debt sustainability, and expanding climate and infrastructure finance, reforms would empower African cities to overcome structural financing barriers while strengthening the African Continental Free Trade Area (AfCFTA). PDBs, as financiers, facilitators, and innovation partners, are uniquely positioned to drive inclusive growth. Their success, underpinned by global reforms, will shape the continent’s ability to build resilient, integrated, and sustainable cities that deliver shared prosperity.